Moon sign

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Moon Signs
Additional zone		Effect		Effect		Effect
friendly Degrassi Knoll	Mongoose	+20% Physical Damage	Wallaby	+20% Spell Damage	Vole	+20% Combat Initiative, +20 Maximum HP/MP
Little Canadia	Platypus	Familiar Weight +5 lbs.	Opossum	+5 Adv. from first food/day	Marmot	Slight Resistance to All Elements (+1)
Gnomish Gnomad Camp	Wombat	+20% Meat from Monsters	Blender	+5 Adv. from first booze/day	Packrat	+10% Items from Monsters
Hey Deze	Bad Moon	Many crazy adventures

Once you ascend, you have to choose a zodiac sign. There are signs for each of the three stat classes and they all cause individual, minor changes to gameplay. Your choice is not limited to the class you choose to play as (for example, you can be a Seal Clubber while having a Mysticality sign). While the general benefits of most of these signs has now been determined, quantifiable details still remain elusive. In total, there are nine signs to choose from (plus a tenth that can be unlocked):

Muscle signs:

• The Mongoose - Sometimes gives a bonus of a few Muscle stat subpoints after a battle.
• The Wallaby - Gives your familiar an occasional boost to its weight, but only on an auto-attack.
• The Vole - The Vole adds an extra .5x multiplier to the chance of critical hit. The forum discussion thread can be found here.

The Muscle signs give you access to Inside Degrassi Knoll in the The Nearby Plains.

Mysticality signs:

• The Platypus - Sometimes gives a bonus of a few Mysticality stat subpoints after a battle.
• The Opossum - Increases adventure gains from food consumption. +0-3 adventures per food, depending on quality of consumed item.
• The Marmot - Gives a ten-leaf clover as an added bonus after a non-combat adventure 2.5% of the time.

The Mysticality signs give you access to Little Canadia just outside of the Seaside Town.

Moxie signs:

• The Wombat - Sometimes gives a bonus of a few Moxie stat subpoints after a battle.
• The Blender - Increases adventure gains from booze consumption. +0-1 adventures per booze.
• The Packrat - Was believed to increase item drop rate. This has fallen under suspicion and requires further testing. It is also hypothesized that it increases meat gains.

The Moxie signs give you access to The Gnomish Gnomads' Camp at the Desert Beach.

Other signs:

• Bad Moon - Unlocked by not using any clovers on one's previous run. Seals familiars and ascension awards from prior ascension until the king is freed, other effects not yet known.

Notes

• The usefulness of certain sign benefits may vary for characters following certain paths; for example the Blender is totally worthless if you are a Teetotaler or Oxygenarian.
• The ability to access the zodiac-specific areas only lasts for the current Ascension. Choosing a sign of a different stat class will close off the previous area again.
• Apparently, the cause of all the astrological signs being transformations of each other is that all the signs are the same - the character is just facing different directions when ascending.

References

• Refers to Astrological signs, also known as Zodiac signs.